The design aim was to create a hospital, whose functionality and layout would help easy relationships between patients, personnel and visitors. The total area of the building is 50,000m² and it accommodates 420 beds.

The basement hosts a 600 visitors and staff car parking. The Henry Dunant is the first General Surgery Hospital in Greece with modern data processing systems. The architectural concept is clearly indentified by the cross shape of the four top nursing floors, seated, on top of a building structure with octagonal floor plan, deployed on three overground and two underground levels, serving diagnostic, therapeutic and ancillary functions.

The departments are arranged around a central core, to be the starting point for all traffic. The shape of the hospital allows all floor departments to be served through a central core of elevators and staircases.